Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Lcin_0234Naringenin-chalcone synthase. (367 aa)    
Predicted Functional Partners:
Lcin_0233
Methyltransferase.
 
     0.927
rkpA
Type I polyketide synthase WcbR.
  
 
 0.885
Lcin_0232
FAD dependent oxidoreductase.
 
  
 0.853
phrB
Deoxyribodipyrimidine photolyase phrB; Belongs to the DNA photolyase family.
    
   0.738
Lcin_2984
Metallo-beta-lactamase.
    
 0.687
tycC_2
Non-ribosomal peptide synthase.
  
 
 0.683
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.631
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.631
echA8_1
enoyl-CoA hydratase.
    
 0.579
Lcin_0265
Transmembrane protein.
    
  0.577
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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