Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pbpCPenicillin binding protein 1C. (768 aa)    
Predicted Functional Partners:
Lcin_0236
Hypothetical protein; Alpha-2-macroglobulin family N-terminal region.
   
 0.979
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.899
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
 0.899
mrcA
Putative peptidoglycan synthetase, penicillin-binding protein 1A.
  
  
0.886
dacB_2
D-Ala-D-Ala carboxypeptidase.
     
 0.861
dacB_1
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
     
 0.861
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
     
 0.855
dap
Beta-lactamase.
     
  0.544
Lcin_2571
D-alanyl-D-alanine carboxypeptidase.
     
  0.544
ampH
Putative secreted esterase.
     
  0.544
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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