secA_1 protein (Legionella cincinnatiensis) - STRING interaction network

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[Homology]

Score

secA_1

Coiled-coil protein. (2233 aa)

Predicted Functional Partners:

secY

0.872

secG

0.839

secB

0.835

Lcin_0239

0.773

Lcin_0001

0.708

secE

0.708

polA

0.702

rplW

0.588

rpmC

0.586

secD

0.563

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0001	rplW	Lcin_0001	Lcin_0639	Ankyrin repeat protein.	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.831
Lcin_0001	rpmC	Lcin_0001	Lcin_0633	Ankyrin repeat protein.	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.727
Lcin_0001	secA_1	Lcin_0001	Lcin_0240	Ankyrin repeat protein.	Coiled-coil protein.	0.708
Lcin_0001	secB	Lcin_0001	Lcin_1881	Ankyrin repeat protein.	Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.	0.589
Lcin_0001	secD	Lcin_0001	Lcin_1442	Ankyrin repeat protein.	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.	0.932
Lcin_0001	secG	Lcin_0001	Lcin_0779	Ankyrin repeat protein.	Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.969
Lcin_0001	secY	Lcin_0001	Lcin_0621	Ankyrin repeat protein.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.970
Lcin_0239	secA_1	Lcin_0239	Lcin_0240	Hypothetical protein.	Coiled-coil protein.	0.773
polA	secA_1	Lcin_2654	Lcin_0240	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Coiled-coil protein.	0.702
polA	secD	Lcin_2654	Lcin_1442	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.	0.505
polA	secG	Lcin_2654	Lcin_0779	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.521
polA	secY	Lcin_2654	Lcin_0621	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.489
rplW	Lcin_0001	Lcin_0639	Lcin_0001	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Ankyrin repeat protein.	0.831
rplW	rpmC	Lcin_0639	Lcin_0633	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.999
rplW	secA_1	Lcin_0639	Lcin_0240	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Coiled-coil protein.	0.588
rplW	secE	Lcin_0639	Lcin_1577	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Preprotein translocase secE subunit.	0.833
rplW	secG	Lcin_0639	Lcin_0779	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.770
rplW	secY	Lcin_0639	Lcin_0621	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.996
rpmC	Lcin_0001	Lcin_0633	Lcin_0001	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	Ankyrin repeat protein.	0.727
rpmC	rplW	Lcin_0633	Lcin_0639	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.999