garR protein (Legionella cincinnatiensis) - STRING interaction network

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Score

garR

3-hydroxyisobutyrate dehydrogenase. (288 aa)

Predicted Functional Partners:

fadB

0.813

yfcX

0.813

echA8_2

0.748

pheA_2

0.695

Hgd

0.691

paaF

0.681

Lcin_1897

0.639

Lcin_0024

0.619

echA8_1

0.618

Lcin_1615

0.605

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hgd	Lcin_0024	Lcin_0099	Lcin_0024	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.588
Hgd	Lcin_1615	Lcin_0099	Lcin_1615	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.	0.605
Hgd	echA8_1	Lcin_0099	Lcin_1538	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	enoyl-CoA hydratase.	0.808
Hgd	echA8_2	Lcin_0099	Lcin_1409	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	enoyl-CoA hydratase.	0.992
Hgd	fadB	Lcin_0099	Lcin_2852	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.813
Hgd	garR	Lcin_0099	Lcin_0263	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	3-hydroxyisobutyrate dehydrogenase.	0.691
Hgd	paaF	Lcin_0099	Lcin_1408	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	enoyl-CoA hydratase.	0.690
Hgd	pheA_2	Lcin_0099	Lcin_2173	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Chorismate mutase.	0.695
Hgd	yfcX	Lcin_0099	Lcin_3310	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.813
Lcin_0024	Hgd	Lcin_0024	Lcin_0099	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.588
Lcin_0024	Lcin_1897	Lcin_0024	Lcin_1897	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Phosphatase.	0.574
Lcin_0024	fadB	Lcin_0024	Lcin_2852	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.425
Lcin_0024	garR	Lcin_0024	Lcin_0263	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	3-hydroxyisobutyrate dehydrogenase.	0.619
Lcin_0024	yfcX	Lcin_0024	Lcin_3310	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.425
Lcin_1615	Hgd	Lcin_1615	Lcin_0099	Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.605
Lcin_1615	fadB	Lcin_1615	Lcin_2852	Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.	3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.536
Lcin_1615	garR	Lcin_1615	Lcin_0263	Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.	3-hydroxyisobutyrate dehydrogenase.	0.605
Lcin_1615	yfcX	Lcin_1615	Lcin_3310	Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.	Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.536
Lcin_1897	Lcin_0024	Lcin_1897	Lcin_0024	Phosphatase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.574
Lcin_1897	garR	Lcin_1897	Lcin_0263	Phosphatase.	3-hydroxyisobutyrate dehydrogenase.	0.639