Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
copA_2Multicopper oxidase. (826 aa)    
Predicted Functional Partners:
copA_1
Cation transport ATPase.
 
 0.911
pacS
Cation transport ATPase.
 
 
 0.895
actP
Copper efflux ATPase.
 
 
 0.858
cueO
Multicopper oxidase.
 
  
0.817
cadA
Cadmium efflux ATPase.
 
 
 0.815
tatC
Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
   
 
 0.785
evgS_2
Sensor histidine kinase.
  
 
 0.743
coxB
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.678
tycC_2
Non-ribosomal peptide synthase.
     
 0.648
arcB_4
Sensory box histidine kinase/response regulator.
  
 
 0.616
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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