rpoE protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rpoE

Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)

Predicted Functional Partners:

rpoB

0.825

Lcin_1315

0.820

rpoC

0.817

rpoA

0.806

cheR

0.775

cptB

0.760

rpoZ

0.760

Lcin_0338

0.729

ygfZ

0.644

tycC_2

0.554

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0338	cptB	Lcin_0338	Lcin_0339	Hypothetical protein.	Antitoxin CptB.	0.840
Lcin_0338	rpoE	Lcin_0338	Lcin_0337	Hypothetical protein.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.729
Lcin_0338	ygfZ	Lcin_0338	Lcin_0340	Hypothetical protein.	Glycine cleavage T protein.	0.717
Lcin_1315	rpoE	Lcin_1315	Lcin_0337	Coiled-coil protein.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.820
cheR	rpoE	Lcin_2630	Lcin_0337	Methyltransferase involved in chemotaxis (CheR domain).	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.775
cptB	Lcin_0338	Lcin_0339	Lcin_0338	Antitoxin CptB.	Hypothetical protein.	0.840
cptB	rpoE	Lcin_0339	Lcin_0337	Antitoxin CptB.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.760
cptB	ygfZ	Lcin_0339	Lcin_0340	Antitoxin CptB.	Glycine cleavage T protein.	0.782
rpoA	rpoB	Lcin_0617	Lcin_1571	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoA	rpoC	Lcin_0617	Lcin_1570	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
rpoA	rpoE	Lcin_0617	Lcin_0337	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.806
rpoA	rpoZ	Lcin_0617	Lcin_1419	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.996
rpoB	rpoA	Lcin_1571	Lcin_0617	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoB	rpoC	Lcin_1571	Lcin_1570	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoB	rpoE	Lcin_1571	Lcin_0337	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.825
rpoB	rpoZ	Lcin_1571	Lcin_1419	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.992
rpoB	tycC_2	Lcin_1571	Lcin_1179	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Non-ribosomal peptide synthase.	0.496
rpoC	rpoA	Lcin_1570	Lcin_0617	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
rpoC	rpoB	Lcin_1570	Lcin_1571	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoC	rpoE	Lcin_1570	Lcin_0337	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Sigma factor RpoE (sigma 24); Belongs to the sigma-70 factor family. ECF subfamily.	0.817