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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (621 aa)    
Predicted Functional Partners:
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 0.998
ftsW
Cell division protein ftsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 0.969
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.932
mreB_2
Rod shape determining protein MreB.
 
 
 
 0.885
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
 
 0.879
mrcA
Putative peptidoglycan synthetase, penicillin-binding protein 1A.
  
 
0.856
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
 
 
 0.809
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
0.794
pbpC
Penicillin binding protein 1C.
  
  
 0.761
cphA_1
Cyanophycin synthetase.
  
 
 0.747
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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