rnhB protein (Legionella cincinnatiensis) - STRING interaction network

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Score

rnhB

Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (182 aa)

Predicted Functional Partners:

dnaN

0.941

lpxB

0.929

tycC_2

0.886

Lcin_1849

0.886

Lcin_0503

0.870

queH

0.851

rnhA

0.849

Lcin_1086

0.820

recQ

0.768

thyA

0.733

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0503	Lcin_1849	Lcin_0503	Lcin_1849	Saframycin Mx1 synthetase B.	acyl-CoA synthetase.	0.999
Lcin_0503	rnhB	Lcin_0503	Lcin_0380	Saframycin Mx1 synthetase B.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.870
Lcin_0503	tycC_2	Lcin_0503	Lcin_1179	Saframycin Mx1 synthetase B.	Non-ribosomal peptide synthase.	0.999
Lcin_1086	dnaN	Lcin_1086	Lcin_1043	Eukaryotic DNA topoisomerase I, catalytic core.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.476
Lcin_1086	recQ	Lcin_1086	Lcin_1405	Eukaryotic DNA topoisomerase I, catalytic core.	ATP-dependent DNA helicase.	0.898
Lcin_1086	rnhB	Lcin_1086	Lcin_0380	Eukaryotic DNA topoisomerase I, catalytic core.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.820
Lcin_1849	Lcin_0503	Lcin_1849	Lcin_0503	acyl-CoA synthetase.	Saframycin Mx1 synthetase B.	0.999
Lcin_1849	rnhB	Lcin_1849	Lcin_0380	acyl-CoA synthetase.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.886
Lcin_1849	tycC_2	Lcin_1849	Lcin_1179	acyl-CoA synthetase.	Non-ribosomal peptide synthase.	0.999
dnaN	Lcin_1086	Lcin_1043	Lcin_1086	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Eukaryotic DNA topoisomerase I, catalytic core.	0.476
dnaN	recQ	Lcin_1043	Lcin_1405	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	ATP-dependent DNA helicase.	0.882
dnaN	rnhA	Lcin_1043	Lcin_0372	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.648
dnaN	rnhB	Lcin_1043	Lcin_0380	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.941
dnaN	thyA	Lcin_1043	Lcin_0876	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.796
lpxB	rnhB	Lcin_0382	Lcin_0380	lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.929
queH	rnhB	Lcin_0741	Lcin_0380	Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.851
recQ	Lcin_1086	Lcin_1405	Lcin_1086	ATP-dependent DNA helicase.	Eukaryotic DNA topoisomerase I, catalytic core.	0.898
recQ	dnaN	Lcin_1405	Lcin_1043	ATP-dependent DNA helicase.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.882
recQ	rnhA	Lcin_1405	Lcin_0372	ATP-dependent DNA helicase.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.528
recQ	rnhB	Lcin_1405	Lcin_0380	ATP-dependent DNA helicase.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.768