STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdSPutative type I restriction-modification system (methylase S subunit). (456 aa)    
Predicted Functional Partners:
hsdM_2
Putative type I restriction enzyme M protein.
 
 0.997
hsdR_2
Putative type I restriction enzyme R protein.
 
  
 0.979
hsdM_1
Putative type I restriction enzyme M protein.
 
 
 0.935
Lcin_0418
Prophage maintenance system killer protein.
       0.782
Lcin_0417
Hypothetical protein.
       0.781
Lcin_0415
MerR family regulatory protein.
       0.778
Lcin_0420
Hypothetical protein.
       0.777
hsdR_1
Type-1 restriction system, restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.681
Lcin_0422
P-loop ATPase.
       0.681
Lcin_1462
Hypothetical protein.
   
    0.590
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.