Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_0454Hypothetical protein. (216 aa)    
Predicted Functional Partners:
evgS_2
Sensor histidine kinase.
  
 0.997
arcB_4
Sensory box histidine kinase/response regulator.
  
 0.993
arcB_1
Sensory histidine-kinase / response regulator.
  
 0.993
letS
Legionella transmission sensor LetS.
  
 0.991
cyaB
Guanylate/adenylate cyclase.
   
 0.989
Lcin_3402
LuxR family transcriptional regulator.
  
 0.989
luxQ
Sensor histidine kinase.
   
 0.987
gmr_3
Regulatory protein (GGDEF domain).
   
 0.984
evgS_1
Sensory box histidine kinase/response regulator.
   
 0.977
pilR
Two component response regulator PilR.
 
 0.975
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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