lolD_2-2 protein (Legionella cincinnatiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lolD_2-2

ABC transporter ATP binding protein. (236 aa)

Predicted Functional Partners:

macB_2

0.982

Lcin_0516

0.962

lolE

0.925

macA_2

0.883

ttgC_6

0.877

lolA

0.776

eptA_2

0.661

rpsI

0.655

rpsK

0.631

gcp

0.568

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0516	eptA_2	Lcin_0516	Lcin_0512	FtsX-like permease family protein.	Sulfatase.	0.678
Lcin_0516	lolD_2-2	Lcin_0516	Lcin_0515	FtsX-like permease family protein.	ABC transporter ATP binding protein.	0.962
Lcin_0516	lolE	Lcin_0516	Lcin_1906	FtsX-like permease family protein.	Outer membrane-specific lipoprotein ABC transporter subunit.	0.552
Lcin_0516	macA_2	Lcin_0516	Lcin_0514	FtsX-like permease family protein.	Hemolysin D.	0.978
Lcin_0516	ttgC_6	Lcin_0516	Lcin_0513	FtsX-like permease family protein.	Multidrug efflux MFS outer membrane protein.	0.924
eptA_2	Lcin_0516	Lcin_0512	Lcin_0516	Sulfatase.	FtsX-like permease family protein.	0.678
eptA_2	lolD_2-2	Lcin_0512	Lcin_0515	Sulfatase.	ABC transporter ATP binding protein.	0.661
eptA_2	macA_2	Lcin_0512	Lcin_0514	Sulfatase.	Hemolysin D.	0.678
eptA_2	ttgC_6	Lcin_0512	Lcin_0513	Sulfatase.	Multidrug efflux MFS outer membrane protein.	0.678
gcp	lolD_2-2	Lcin_1211	Lcin_0515	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	ABC transporter ATP binding protein.	0.568
gcp	rpsI	Lcin_1211	Lcin_0715	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.507
gcp	rpsK	Lcin_1211	Lcin_0619	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.415
lolA	lolD_2-2	Lcin_2859	Lcin_0515	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	ABC transporter ATP binding protein.	0.776
lolA	lolE	Lcin_2859	Lcin_1906	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane-specific lipoprotein ABC transporter subunit.	0.964
lolD_2-2	Lcin_0516	Lcin_0515	Lcin_0516	ABC transporter ATP binding protein.	FtsX-like permease family protein.	0.962
lolD_2-2	eptA_2	Lcin_0515	Lcin_0512	ABC transporter ATP binding protein.	Sulfatase.	0.661
lolD_2-2	gcp	Lcin_0515	Lcin_1211	ABC transporter ATP binding protein.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.568
lolD_2-2	lolA	Lcin_0515	Lcin_2859	ABC transporter ATP binding protein.	Outer-membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.776
lolD_2-2	lolE	Lcin_0515	Lcin_1906	ABC transporter ATP binding protein.	Outer membrane-specific lipoprotein ABC transporter subunit.	0.925
lolD_2-2	macA_2	Lcin_0515	Lcin_0514	ABC transporter ATP binding protein.	Hemolysin D.	0.883