Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_0558Putative Antitoxin higA-2. (96 aa)    
Predicted Functional Partners:
higB
Toxin higB-2.
 
 
 
 0.978
Lcin_3023
Hypothetical protein.
  
 
 0.769
ycaC_1
YcaC related amidohydrolase.
   
    0.644
parD1
Putative addiction module antidote protein, family (containing the CopG/Arc/MetJ DNA-binding domain).
  
   
 0.511
higA
Antitoxin HigA.
  
     0.509
Lcin_0556
Protein of unknown function DUF1016.
 
     0.482
Lcin_2734
Hypothetical protein.
  
     0.474
Lcin_1455
Hypothetical protein.
   
 
 0.471
Lcin_3353
Hypothetical protein.
   
 
 0.471
parE1
Putative toxin antitoxin plasmid stabilization system ParE; Belongs to the RelE toxin family.
  
     0.454
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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