Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bepFMembrane-fusion protein involved in transport; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (381 aa)    
Predicted Functional Partners:
czcA_1
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  0.983
oprM_2
Outer membrane efflux protein.
 
  0.918
Lcin_3043
Cation/multidrug efflux pump.
 
  0.913
tolC
Outer membrane protein TolC.
  
 0.888
czcA_2
Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.831
Lcin_0933
Outer membrane efflux protein.
   
  0.825
mdtB
Multidrug efflux system, subunit B; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.812
mdtC
Multidrug efflux system, subunit C; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.798
lmxF
Multidrug efflux pump.
  
  0.793
helA
HelA protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.747
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: low (18%) [HD]