Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dotCDefect in organelle trafficking lipoprotein DotC. (308 aa)    
Predicted Functional Partners:
dotG
IcmE/DotG protein.
  
 
 
 0.982
dotD
Lipoprotein DotD.
   
 
 0.981
yggR_1
DotB.
 
   
 0.969
Lcin_2004
IcmK protein.
 
 
 
 0.962
Lcin_2008
Protein IcmO (DotL).
 
   
 0.853
dotF
Component of the Dot/Icm secretion system.
    
 
 0.842
Lcin_1999
IcmJ protein.
 
   
 0.834
Lcin_1327
Enhanced entry protein EnhA.
  
  
  0.829
Lcin_1998
Protein IcmB (DotO).
  
   
 0.825
enhA_3
Enhanced entry protein EnhA.
  
  
  0.824
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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