Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (171 aa)    
Predicted Functional Partners:
dsbA
Thiol:disulfide interchange protein precursor DsbA.
 
 
 0.974
cycB
Cytochrome c5.
       0.840
dsbG
NHL repeat protein.
  
 
 0.694
hemX
Uroporphyrinogen III methylase HemX.
 
     0.688
com1
27 kDa outer membrane protein.
  
 
 0.656
hemY
Protoporphyrinogen oxidase.
 
     0.640
succ
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
  0.549
sucA
2-oxoglutarate dehydrogenase E1.
     
  0.549
icd
Isocitrate dehydrogenase.
     
  0.548
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
     
  0.538
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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