pepN_2 protein (Legionella cincinnatiensis) - STRING interaction network

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Score

pepN_2

Aminopeptidase. (861 aa)

Predicted Functional Partners:

pepB

0.903

pepA

0.890

glyA

0.877

pepN_1

0.873

gshB

0.863

gshA

0.855

metB

0.852

ybdK_1

0.848

ggt

0.848

cysK

0.848

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cysK	glyA	Lcin_0974	Lcin_1342	Cystathionine beta-synthase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.569
cysK	gshA	Lcin_0974	Lcin_1559	Cystathionine beta-synthase.	Glutamate--cysteine ligase.	0.851
cysK	metB	Lcin_0974	Lcin_1359	Cystathionine beta-synthase.	Cystathionine beta-lyase.	0.994
cysK	pepA	Lcin_0974	Lcin_1245	Cystathionine beta-synthase.	Leucine aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.859
cysK	pepB	Lcin_0974	Lcin_0582	Cystathionine beta-synthase.	Aminopeptidase; Belongs to the peptidase M17 family.	0.859
cysK	pepN_1	Lcin_0974	Lcin_0246	Cystathionine beta-synthase.	Aminopeptidase.	0.848
cysK	pepN_2	Lcin_0974	Lcin_0796	Cystathionine beta-synthase.	Aminopeptidase.	0.848
cysK	ybdK_1	Lcin_0974	Lcin_0423	Cystathionine beta-synthase.	Gamma-glutamyl:cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	0.848
ggt	gshA	Lcin_0656	Lcin_1559	Gamma-glutamyltranspeptidase.	Glutamate--cysteine ligase.	0.848
ggt	gshB	Lcin_0656	Lcin_1558	Gamma-glutamyltranspeptidase.	Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.	0.895
ggt	pepA	Lcin_0656	Lcin_1245	Gamma-glutamyltranspeptidase.	Leucine aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.880
ggt	pepB	Lcin_0656	Lcin_0582	Gamma-glutamyltranspeptidase.	Aminopeptidase; Belongs to the peptidase M17 family.	0.880
ggt	pepN_1	Lcin_0656	Lcin_0246	Gamma-glutamyltranspeptidase.	Aminopeptidase.	0.848
ggt	pepN_2	Lcin_0656	Lcin_0796	Gamma-glutamyltranspeptidase.	Aminopeptidase.	0.848
ggt	ybdK_1	Lcin_0656	Lcin_0423	Gamma-glutamyltranspeptidase.	Gamma-glutamyl:cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.	0.853
glyA	cysK	Lcin_1342	Lcin_0974	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Cystathionine beta-synthase.	0.569
glyA	gshB	Lcin_1342	Lcin_1558	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.	0.850
glyA	pepA	Lcin_1342	Lcin_1245	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Leucine aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.849
glyA	pepB	Lcin_1342	Lcin_0582	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Aminopeptidase; Belongs to the peptidase M17 family.	0.849
glyA	pepN_1	Lcin_1342	Lcin_0246	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Aminopeptidase.	0.874