Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (250 aa)    
Predicted Functional Partners:
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
  
 0.946
Lcin_0919
SCP-2 sterol transfer family protein.
  
  
 0.908
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
   
 
 0.882
ubiB
Ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
  
  
 0.876
tatA
TatA protein(twin arginine translocation); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
 
    0.871
wrbA
Flavoprotein WrbA (Trp repressor binding protein); Belongs to the WrbA family.
     
  0.848
tatB
TatB protein (twin arginine translocation).
  
    0.840
visC
Oxidoreductase with FAD/NAD(P)-binding domain protein.
  
  
 0.824
tycC_2
Non-ribosomal peptide synthase.
    
 0.721
ispB-2
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.701
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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