Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (271 aa)    
Predicted Functional Partners:
Lcin_2239
Hypothetical protein.
   
 0.972
Lcin_2984
Metallo-beta-lactamase.
    
  0.873
macB_2
ABC transporter permease.
       0.840
macB_1
ABC transporter ATP-binding protein.
       0.840
acrA_1
Membrane-fusion protein AcrA.
       0.840
Lcin_0933
Outer membrane efflux protein.
       0.840
Lcin_0935
Putative helicase/relaxase.
       0.840
mip
Macrophage infectivity potentiator.
    
 0.839
ksgA
Dimethyladenosine transferase (16S rRNA dimethylase); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.823
yjeA
Endo-1,4-beta-xylanase.
   
 0.782
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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