Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_1107Cyclic nucleotide-binding protein. (370 aa)    
Predicted Functional Partners:
Lcin_2239
Hypothetical protein.
    
  0.822
Lcin_1106
Hypothetical protein.
       0.785
Lcin_1108
Reverse transcriptase (RNA-dependent DNA polymerase).
       0.773
crp_1
Cyclic nucleotide-binding protein.
  
  
  0.702
cyaB
Guanylate/adenylate cyclase.
 
 0.702
cyaA_1
Guanylate cyclase.
 
 
 0.700
evgS_2
Sensor histidine kinase.
   
 0.670
cyaA_2
Guanylate/adenylate cyclase.
 
 
 
 0.648
cyaA_7
Guanylate cyclase.
 
 
 
 0.641
Lcin_1105
Hypothetical protein.
       0.620
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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