ppaX protein (Legionella cincinnatiensis) - STRING interaction network

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Score

ppaX

HAD-superfamily hydrolase. (211 aa)

Predicted Functional Partners:

Lcin_1897

0.922

pheA_2

0.578

Lcin_0024

0.557

guaA

0.547

rpe

0.498

Lcin_1142

0.494

Lcin_1730

0.483

dprE1_2

0.475

dprE1_1

0.475

ribD

0.470

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0024	Lcin_1897	Lcin_0024	Lcin_1897	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Phosphatase.	0.558
Lcin_0024	dprE1_1	Lcin_0024	Lcin_2399	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Hypothetical protein.	0.547
Lcin_0024	dprE1_2	Lcin_0024	Lcin_0522	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Oxidoreductase.	0.547
Lcin_0024	ppaX	Lcin_0024	Lcin_1141	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	HAD-superfamily hydrolase.	0.557
Lcin_1142	ppaX	Lcin_1142	Lcin_1141	Hypothetical protein.	HAD-superfamily hydrolase.	0.494
Lcin_1730	Lcin_1897	Lcin_1730	Lcin_1897	Putative phosphotransferase.	Phosphatase.	0.537
Lcin_1730	ppaX	Lcin_1730	Lcin_1141	Putative phosphotransferase.	HAD-superfamily hydrolase.	0.483
Lcin_1897	Lcin_0024	Lcin_1897	Lcin_0024	Phosphatase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.558
Lcin_1897	Lcin_1730	Lcin_1897	Lcin_1730	Phosphatase.	Putative phosphotransferase.	0.537
Lcin_1897	dprE1_1	Lcin_1897	Lcin_2399	Phosphatase.	Hypothetical protein.	0.475
Lcin_1897	dprE1_2	Lcin_1897	Lcin_0522	Phosphatase.	Oxidoreductase.	0.475
Lcin_1897	guaA	Lcin_1897	Lcin_2940	Phosphatase.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.547
Lcin_1897	pheA_2	Lcin_1897	Lcin_2173	Phosphatase.	Chorismate mutase.	0.578
Lcin_1897	ppaX	Lcin_1897	Lcin_1141	Phosphatase.	HAD-superfamily hydrolase.	0.922
Lcin_1897	ribD	Lcin_1897	Lcin_2464	Phosphatase.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.470
dprE1_1	Lcin_0024	Lcin_2399	Lcin_0024	Hypothetical protein.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.547
dprE1_1	Lcin_1897	Lcin_2399	Lcin_1897	Hypothetical protein.	Phosphatase.	0.475
dprE1_1	ppaX	Lcin_2399	Lcin_1141	Hypothetical protein.	HAD-superfamily hydrolase.	0.475
dprE1_2	Lcin_0024	Lcin_0522	Lcin_0024	Oxidoreductase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.547
dprE1_2	Lcin_1897	Lcin_0522	Lcin_1897	Oxidoreductase.	Phosphatase.	0.475