| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lcin_1271 | era | Lcin_1271 | Lcin_1268 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.605 |
| Lcin_1271 | pdxJ | Lcin_1271 | Lcin_1270 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.810 |
| Lcin_1271 | recO | Lcin_1271 | Lcin_1269 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.613 |
| Lcin_1271 | recR | Lcin_1271 | Lcin_0748 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Recombination and repair protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.550 |
| Lcin_1271 | topA | Lcin_1271 | Lcin_0190 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.995 |
| Lcin_2864 | ftsB | Lcin_2864 | Lcin_3069 | Transmembrane protein. | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.541 |
| Lcin_2864 | recO | Lcin_2864 | Lcin_1269 | Transmembrane protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.711 |
| Lcin_2864 | sspB | Lcin_2864 | Lcin_0710 | Transmembrane protein. | Stringent starvation protein B. | 0.409 |
| era | Lcin_1271 | Lcin_1268 | Lcin_1271 | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.605 |
| era | pdxJ | Lcin_1268 | Lcin_1270 | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.690 |
| era | recO | Lcin_1268 | Lcin_1269 | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.916 |
| era | topA | Lcin_1268 | Lcin_0190 | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.420 |
| era | ybeZ | Lcin_1268 | Lcin_3274 | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphate starvation-inducible protein PhoH. | 0.489 |
| ftsB | Lcin_2864 | Lcin_3069 | Lcin_2864 | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Transmembrane protein. | 0.541 |
| ftsB | recO | Lcin_3069 | Lcin_1269 | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.659 |
| ftsB | sspB | Lcin_3069 | Lcin_0710 | Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Stringent starvation protein B. | 0.719 |
| pdxJ | Lcin_1271 | Lcin_1270 | Lcin_1271 | Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.810 |
| pdxJ | era | Lcin_1270 | Lcin_1268 | Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.690 |
| pdxJ | recO | Lcin_1270 | Lcin_1269 | Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.690 |
| recF | recO | Lcin_1042 | Lcin_1269 | RecF recombinational DNA repair ATPase; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.851 |