| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lcin_1339 | Lcin_1340 | Lcin_1339 | Lcin_1340 | Hypothetical protein. | Hypothetical protein. | 0.666 |
| Lcin_1339 | acrA | Lcin_1339 | Lcin_1338 | Hypothetical protein. | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.679 |
| Lcin_1339 | glyA | Lcin_1339 | Lcin_1342 | Hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.611 |
| Lcin_1339 | nrdR | Lcin_1339 | Lcin_1343 | Hypothetical protein. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.611 |
| Lcin_1339 | osmY | Lcin_1339 | Lcin_1341 | Hypothetical protein. | Lipoprotein. | 0.627 |
| Lcin_1340 | Lcin_1339 | Lcin_1340 | Lcin_1339 | Hypothetical protein. | Hypothetical protein. | 0.666 |
| Lcin_1340 | acrA | Lcin_1340 | Lcin_1338 | Hypothetical protein. | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.426 |
| Lcin_1340 | glyA | Lcin_1340 | Lcin_1342 | Hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.645 |
| Lcin_1340 | nrdR | Lcin_1340 | Lcin_1343 | Hypothetical protein. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.645 |
| Lcin_1340 | osmY | Lcin_1340 | Lcin_1341 | Hypothetical protein. | Lipoprotein. | 0.706 |
| acrA | Lcin_1339 | Lcin_1338 | Lcin_1339 | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Hypothetical protein. | 0.679 |
| acrA | Lcin_1340 | Lcin_1338 | Lcin_1340 | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Hypothetical protein. | 0.426 |
| acrA | glyA | Lcin_1338 | Lcin_1342 | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.465 |
| acrA | nrdR | Lcin_1338 | Lcin_1343 | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.465 |
| acrA | osmY | Lcin_1338 | Lcin_1341 | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Lipoprotein. | 0.556 |
| glyA | Lcin_1339 | Lcin_1342 | Lcin_1339 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.611 |
| glyA | Lcin_1340 | Lcin_1342 | Lcin_1340 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.645 |
| glyA | acrA | Lcin_1342 | Lcin_1338 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.465 |
| glyA | nrdR | Lcin_1342 | Lcin_1343 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.840 |
| glyA | osmY | Lcin_1342 | Lcin_1341 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Lipoprotein. | 0.802 |