osmY protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

osmY

Lipoprotein. (102 aa)

Predicted Functional Partners:

glyA

0.802

nrdR

0.802

Lcin_1892

0.712

Lcin_2329

0.712

Lcin_1340

0.706

yjbJ_1

0.706

yjbJ_2

0.705

yjbJ_3

0.703

putA

0.702

nusB

0.658

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_1340	glyA	Lcin_1340	Lcin_1342	Hypothetical protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.645
Lcin_1340	nrdR	Lcin_1340	Lcin_1343	Hypothetical protein.	Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.	0.645
Lcin_1340	osmY	Lcin_1340	Lcin_1341	Hypothetical protein.	Lipoprotein.	0.706
Lcin_1892	Lcin_2329	Lcin_1892	Lcin_2329	Transmembrane protein.	Transmembrane protein.	0.428
Lcin_1892	osmY	Lcin_1892	Lcin_1341	Transmembrane protein.	Lipoprotein.	0.712
Lcin_1892	yjbJ_1	Lcin_1892	Lcin_2335	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.670
Lcin_1892	yjbJ_2	Lcin_1892	Lcin_3190	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.663
Lcin_1892	yjbJ_3	Lcin_1892	Lcin_3383	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.661
Lcin_2329	Lcin_1892	Lcin_2329	Lcin_1892	Transmembrane protein.	Transmembrane protein.	0.428
Lcin_2329	osmY	Lcin_2329	Lcin_1341	Transmembrane protein.	Lipoprotein.	0.712
Lcin_2329	yjbJ_1	Lcin_2329	Lcin_2335	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.605
Lcin_2329	yjbJ_2	Lcin_2329	Lcin_3190	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.605
Lcin_2329	yjbJ_3	Lcin_2329	Lcin_3383	Transmembrane protein.	Stress response protein; Belongs to the UPF0337 (CsbD) family.	0.605
glyA	Lcin_1340	Lcin_1342	Lcin_1340	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Hypothetical protein.	0.645
glyA	nrdR	Lcin_1342	Lcin_1343	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.	0.840
glyA	nusB	Lcin_1342	Lcin_1344	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	0.696
glyA	osmY	Lcin_1342	Lcin_1341	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Lipoprotein.	0.802
nrdR	Lcin_1340	Lcin_1343	Lcin_1340	Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.	Hypothetical protein.	0.645
nrdR	glyA	Lcin_1343	Lcin_1342	Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.840
nrdR	nusB	Lcin_1343	Lcin_1344	Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	0.814