Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilQType IV pilus (Tfp) assembly protein PilQ. (695 aa)    
Predicted Functional Partners:
pilN
Tfp pilus assembly protein PilN.
 
 
 0.997
pilP
Tfp pilus assembly protein PilP.
 
 
 0.996
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 0.993
pilO
Tfp pilus assembly protein PilO.
 
 
 0.991
pilC
Pilus assembly protein PilC.
 
 
 
 0.858
pilE_1
Type-IV pilin.
 
   
 0.821
pilB
Pilus assembly protein PilB.
 
 
 
 0.813
pilE_2
Tfp pilus assembly protein, major type IV pilin class A; Belongs to the N-Me-Phe pilin family.
 
   
 0.812
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
      
 0.796
lspD
Type II protein secretion LspD.
 
  
0.788
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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