yicC protein (Legionella cincinnatiensis) - STRING interaction network

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Score

yicC

Putative stress-induced protein. (288 aa)

Predicted Functional Partners:

gmk

0.910

rpoZ

0.794

coaD

0.589

rph

0.566

spoT

0.441

tdcF

0.441

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
coaD	gmk	Lcin_0657	Lcin_1418	Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.475
coaD	yicC	Lcin_0657	Lcin_1417	Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	Putative stress-induced protein.	0.589
gmk	coaD	Lcin_1418	Lcin_0657	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	0.475
gmk	rph	Lcin_1418	Lcin_1416	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.634
gmk	rpoZ	Lcin_1418	Lcin_1419	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.982
gmk	spoT	Lcin_1418	Lcin_1420	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.776
gmk	tdcF	Lcin_1418	Lcin_1421	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	L-PSP (mRNA) endoribonuclease.	0.648
gmk	yicC	Lcin_1418	Lcin_1417	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative stress-induced protein.	0.910
rph	gmk	Lcin_1416	Lcin_1418	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.634
rph	rpoZ	Lcin_1416	Lcin_1419	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.542
rph	tdcF	Lcin_1416	Lcin_1421	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	L-PSP (mRNA) endoribonuclease.	0.805
rph	yicC	Lcin_1416	Lcin_1417	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Putative stress-induced protein.	0.566
rpoZ	gmk	Lcin_1419	Lcin_1418	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.982
rpoZ	rph	Lcin_1419	Lcin_1416	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.542
rpoZ	spoT	Lcin_1419	Lcin_1420	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.559
rpoZ	tdcF	Lcin_1419	Lcin_1421	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	L-PSP (mRNA) endoribonuclease.	0.492
rpoZ	yicC	Lcin_1419	Lcin_1417	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Putative stress-induced protein.	0.794
spoT	gmk	Lcin_1420	Lcin_1418	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.776
spoT	rpoZ	Lcin_1420	Lcin_1419	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.559
spoT	tdcF	Lcin_1420	Lcin_1421	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	L-PSP (mRNA) endoribonuclease.	0.792