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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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thiGThiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (260 aa)    
Predicted Functional Partners:
thiS
Thiamine biosynthesis protein ThiS.
 
 0.999
thiDE
Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiO
Thiamine biosynthesis oxidoreductase ThiO.
 
 
 0.995
moeZ_3
Putative molybdenum cofactor synthesis protein 3.
 
 
 0.986
moeZ_2
Thiazole biosynthesis adenylyltransferase ThiF.
 
 
 0.975
thiD
Bifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase.
 
 
 0.950
thi
Thiamine biosynthesis protein NMT-1.
  
    0.842
thiO_2
FAD dependent oxidoreductase.
  
 
 0.809
iscS
Cysteine desulfurase.
    
 0.774
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ). Belongs to the Thz kinase family.
  
 
 0.738
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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