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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moeZ_2Thiazole biosynthesis adenylyltransferase ThiF. (358 aa)    
Predicted Functional Partners:
thiS
Thiamine biosynthesis protein ThiS.
 
 0.983
thiDE
Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.974
thiG
Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.972
iscS
Cysteine desulfurase.
   
 0.875
yibN_2
Rhodanese domain protein.
 
   
 0.858
Lcin_2239
Hypothetical protein.
   
 0.838
moeZ_3
Putative molybdenum cofactor synthesis protein 3.
  
  
0.746
cysK
Cystathionine beta-synthase.
  
 0.679
trxB
Thioredoxin reductase.
  
  
 0.657
thiD
Bifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase.
 
  
 0.655
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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