Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cadACadmium efflux ATPase. (635 aa)    
Predicted Functional Partners:
copA_1
Cation transport ATPase.
 
0.910
copA_2
Multicopper oxidase.
 
 
 0.815
cueO
Multicopper oxidase.
 
 
 0.654
Lcin_1157
Calcium-transporting ATPase.
    
  0.434
mgtA
Magnesium transporter.
    
  0.434
yloB
Cation transport ATPase.
    
  0.434
pacL
Cation efflux transporter.
    
  0.434
uup_2
ABC transporter ATP-binding protein Uup.
       0.419
czrA
Transcriptional regulator, ArsR family.
 
  
 0.412
helC
HelC protein.
  
    0.412
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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