Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Lcin_1493ATP-dependent DNA helicase. (504 aa)    
Predicted Functional Partners:
noc
Nucleoid occlusion protein; Belongs to the ParB family.
 
     0.648
Lcin_1497
Initiator Replication protein.
 
     0.647
traI_3
Putative conjugative transfer protein TraI.
  
     0.587
oprB
Porin B precursor.
  
     0.571
Lcin_1202
Hypothetical protein.
  
     0.570
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
  0.550
Lcin_3028
D12 class N6 adenine-specific DNA methyltransferase.
  
     0.549
Lcin_1201
Hypothetical protein.
  
     0.540
Lcin_1661
Protein kinase.
  
     0.534
Lcin_0402
Hypothetical protein.
  
     0.531
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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