Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mvaBhydroxymethylglutaryl-CoA lyase. (302 aa)    
Predicted Functional Partners:
echA8_1
enoyl-CoA hydratase.
 
 0.997
mccA
Acyl CoA carboxylase subunit alpha.
 
 
 0.979
acsA
acetyl-CoA synthetase.
 
 
 0.971
Lcin_1537
Acetyl/propionyl-CoA carboxylase, beta subunit.
 
 0.969
atoB
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.954
mvaA
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
    
  0.930
echA8_2
enoyl-CoA hydratase.
  
 
 0.910
fadA
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.893
yfcY
beta-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.893
Lcin_1271
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.889
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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