rmlB protein (Legionella cincinnatiensis) - STRING interaction network

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rmlB

dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa)

Predicted Functional Partners:

rmlA2

0.999

rmlC

0.994

rmlD

0.969

wzxE

0.953

arnB

0.934

rmlD-2

0.914

rmlA1

0.865

wbbL

0.832

rfbF

0.813

glmU

0.767

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
arnB	glmU	Lcin_3289	Lcin_0867	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.665
arnB	rfbF	Lcin_3289	Lcin_0835	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	0.625
arnB	rmlA1	Lcin_3289	Lcin_1729	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Nucleotidyltransferase.	0.634
arnB	rmlA2	Lcin_3289	Lcin_1631	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.692
arnB	rmlB	Lcin_3289	Lcin_1632	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.934
arnB	rmlC	Lcin_3289	Lcin_0529	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.718
arnB	wbbL	Lcin_3289	Lcin_0496	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Putative glycosyl transferase.	0.465
arnB	wzxE	Lcin_3289	Lcin_0827	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	Lipopolysaccharide biosynthesis protein.	0.417
glmU	arnB	Lcin_0867	Lcin_3289	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	0.665
glmU	rfbF	Lcin_0867	Lcin_0835	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	0.675
glmU	rmlA1	Lcin_0867	Lcin_1729	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Nucleotidyltransferase.	0.693
glmU	rmlA2	Lcin_0867	Lcin_1631	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.653
glmU	rmlB	Lcin_0867	Lcin_1632	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.767
glmU	rmlC	Lcin_0867	Lcin_0529	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.407
rfbF	arnB	Lcin_0835	Lcin_3289	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.	0.625
rfbF	glmU	Lcin_0835	Lcin_0867	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.675
rfbF	rmlA1	Lcin_0835	Lcin_1729	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	Nucleotidyltransferase.	0.632
rfbF	rmlA2	Lcin_0835	Lcin_1631	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.834
rfbF	rmlB	Lcin_0835	Lcin_1632	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.813
rfbF	rmlC	Lcin_0835	Lcin_0529	Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase).	dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.852

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