Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
budBAcetolactate synthase; Belongs to the TPP enzyme family. (546 aa)    
Predicted Functional Partners:
porB
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
 0.936
Lcin_1271
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.907
sfcA_1
Malate dehydrogenase.
   
 0.878
maeB
NADP-dependent malic enzyme.
   
 0.878
sfcA_2
Malate oxidoreductase.
   
 0.878
lldD
FMN-dependent dehydrogenase.
    
 0.869
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.868
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.865
aceE
Pyruvate dehydrogenase (decarboxylase component) E1p; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.855
pta
Phosphate acetyl/butaryl transferase.
  
 0.838
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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