pieE_2 protein (Legionella cincinnatiensis) - STRING interaction network

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Score

pieE_2

Substrate of the Dot/Icm secretion system. (581 aa)

Predicted Functional Partners:

map_2

0.767

rpsN

0.650

dksA

0.601

rpmB

0.506

rpmG

0.423

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dksA	pieE_2	Lcin_1862	Lcin_1648	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Substrate of the Dot/Icm secretion system.	0.601
map_2	pieE_2	Lcin_2943	Lcin_1648	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Substrate of the Dot/Icm secretion system.	0.767
map_2	rpsN	Lcin_2943	Lcin_0628	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.980
pieE_2	dksA	Lcin_1648	Lcin_1862	Substrate of the Dot/Icm secretion system.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.601
pieE_2	map_2	Lcin_1648	Lcin_2943	Substrate of the Dot/Icm secretion system.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.767
pieE_2	rpmB	Lcin_1648	Lcin_2802	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.506
pieE_2	rpmG	Lcin_1648	Lcin_2801	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.423
pieE_2	rpsN	Lcin_1648	Lcin_0628	Substrate of the Dot/Icm secretion system.	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.650
rpmB	pieE_2	Lcin_2802	Lcin_1648	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	Substrate of the Dot/Icm secretion system.	0.506
rpmB	rpmG	Lcin_2802	Lcin_2801	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.999
rpmB	rpsN	Lcin_2802	Lcin_0628	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.996
rpmG	pieE_2	Lcin_2801	Lcin_1648	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	Substrate of the Dot/Icm secretion system.	0.423
rpmG	rpmB	Lcin_2801	Lcin_2802	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.999
rpmG	rpsN	Lcin_2801	Lcin_0628	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.993
rpsN	map_2	Lcin_0628	Lcin_2943	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.980
rpsN	pieE_2	Lcin_0628	Lcin_1648	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	Substrate of the Dot/Icm secretion system.	0.650
rpsN	rpmB	Lcin_0628	Lcin_2802	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.996
rpsN	rpmG	Lcin_0628	Lcin_2801	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.993