Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sidJSubstrate of the Dot/Icm secretion system. (863 aa)    
Predicted Functional Partners:
wipB
Substrate of the Dot/Icm secretion system.
      
 0.698
Lcin_2441
Ubiquitin-like protease.
      
 0.698
laiE
SdeA protein.
     
 0.669
ankK
Substrate of the Dot/Icm secretion system.
      
 0.656
Lcin_0519
Chromosome segregation protein.
      
 0.618
lepB_2
Signal peptidase I; Belongs to the peptidase S26 family.
      
 0.618
cpxR_3
Transcriptional regulatory protein CpxR.
      
 0.568
Lcin_3420
IcmF.
      
 0.474
sidE
SidE protein.
    
   0.450
Lcin_1619
Hypothetical protein.
    
   0.450
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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