Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
sfcA_1Malate dehydrogenase. (569 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.889
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.884
Lcin_1271
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.884
budB
Acetolactate synthase; Belongs to the TPP enzyme family.
   
 0.878
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.877
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.866
porB
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.859
Lcin_0024
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
     
 0.857
aceE
Pyruvate dehydrogenase (decarboxylase component) E1p; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.856
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.855
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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