macA_1 protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

macA_1

Hemolysin D. (277 aa)

Predicted Functional Partners:

ybhS

0.966

ybhF

0.966

oprM_1

0.908

tolC

0.770

Lcin_0933

0.747

acrA

0.679

macB_2

0.672

acrA_1

0.650

mdtE_1

0.626

mexA

0.622

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0933	acrA	Lcin_0933	Lcin_1338	Outer membrane efflux protein.	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.943
Lcin_0933	acrA_1	Lcin_0933	Lcin_0932	Outer membrane efflux protein.	Membrane-fusion protein AcrA.	0.982
Lcin_0933	macA_1	Lcin_0933	Lcin_1707	Outer membrane efflux protein.	Hemolysin D.	0.747
Lcin_0933	macB_2	Lcin_0933	Lcin_0930	Outer membrane efflux protein.	ABC transporter permease.	0.935
Lcin_0933	mdtE_1	Lcin_0933	Lcin_1625	Outer membrane efflux protein.	Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.943
Lcin_0933	mexA	Lcin_0933	Lcin_2017	Outer membrane efflux protein.	Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.943
Lcin_0933	tolC	Lcin_0933	Lcin_1322	Outer membrane efflux protein.	Outer membrane protein TolC.	0.932
acrA	Lcin_0933	Lcin_1338	Lcin_0933	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane efflux protein.	0.943
acrA	acrA_1	Lcin_1338	Lcin_0932	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Membrane-fusion protein AcrA.	0.744
acrA	macA_1	Lcin_1338	Lcin_1707	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Hemolysin D.	0.679
acrA	macB_2	Lcin_1338	Lcin_0930	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	ABC transporter permease.	0.633
acrA	mdtE_1	Lcin_1338	Lcin_1625	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.830
acrA	mexA	Lcin_1338	Lcin_2017	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.970
acrA	oprM_1	Lcin_1338	Lcin_1704	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane efflux protein.	0.502
acrA	tolC	Lcin_1338	Lcin_1322	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.968
acrA_1	Lcin_0933	Lcin_0932	Lcin_0933	Membrane-fusion protein AcrA.	Outer membrane efflux protein.	0.982
acrA_1	acrA	Lcin_0932	Lcin_1338	Membrane-fusion protein AcrA.	RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.744
acrA_1	macA_1	Lcin_0932	Lcin_1707	Membrane-fusion protein AcrA.	Hemolysin D.	0.650
acrA_1	macB_2	Lcin_0932	Lcin_0930	Membrane-fusion protein AcrA.	ABC transporter permease.	0.964
acrA_1	mdtE_1	Lcin_0932	Lcin_1625	Membrane-fusion protein AcrA.	Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.698