| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lcin_1554 | secB | Lcin_1554 | Lcin_1881 | Ankyrin repeat-containing protein. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.860 |
| Lcin_1554 | secE | Lcin_1554 | Lcin_1577 | Ankyrin repeat-containing protein. | Preprotein translocase secE subunit. | 0.799 |
| Lcin_1554 | secG | Lcin_1554 | Lcin_0779 | Ankyrin repeat-containing protein. | Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.870 |
| Lcin_1554 | yidC | Lcin_1554 | Lcin_1047 | Ankyrin repeat-containing protein. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.558 |
| grx | secB | Lcin_1882 | Lcin_1881 | Glutaredoxin Grx; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.963 |
| grx | yibN | Lcin_1882 | Lcin_1883 | Glutaredoxin Grx; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Rhodanese-related sulfurtransferase. | 0.894 |
| secA | secB | Lcin_3237 | Lcin_1881 | Preprotein translocase, secretion protein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.975 |
| secA | secE | Lcin_3237 | Lcin_1577 | Preprotein translocase, secretion protein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | Preprotein translocase secE subunit. | 0.878 |
| secA | secG | Lcin_3237 | Lcin_0779 | Preprotein translocase, secretion protein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.964 |
| secA | yajC | Lcin_3237 | Lcin_1441 | Preprotein translocase, secretion protein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | SecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.686 |
| secA | yidC | Lcin_3237 | Lcin_1047 | Preprotein translocase, secretion protein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.710 |
| secA_1 | secB | Lcin_0240 | Lcin_1881 | Coiled-coil protein. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.901 |
| secA_1 | secE | Lcin_0240 | Lcin_1577 | Coiled-coil protein. | Preprotein translocase secE subunit. | 0.786 |
| secA_1 | secG | Lcin_0240 | Lcin_0779 | Coiled-coil protein. | Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.877 |
| secA_1 | yajC | Lcin_0240 | Lcin_1441 | Coiled-coil protein. | SecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.413 |
| secA_1 | yidC | Lcin_0240 | Lcin_1047 | Coiled-coil protein. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.459 |
| secA_3 | secB | Lcin_2605 | Lcin_1881 | Coiled-coil protein. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.901 |
| secA_3 | secE | Lcin_2605 | Lcin_1577 | Coiled-coil protein. | Preprotein translocase secE subunit. | 0.786 |
| secA_3 | secG | Lcin_2605 | Lcin_0779 | Coiled-coil protein. | Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.877 |
| secA_3 | yajC | Lcin_2605 | Lcin_1441 | Coiled-coil protein. | SecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.413 |
STRING v12.5 is now available!
