Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_2005Protein IcmL (DotI). (212 aa)    
Predicted Functional Partners:
Lcin_2004
IcmK protein.
 
   
 0.954
dotG
IcmE/DotG protein.
 
   
 0.945
Lcin_1998
Protein IcmB (DotO).
 
   
 0.912
Lcin_1999
IcmJ protein.
 
   
 0.911
Lcin_2008
Protein IcmO (DotL).
 
   
 0.880
Lcin_2009
IcmP protein.
 
   
 0.875
icmM
IcmM (DotJ).
     
 0.859
lphA
LphA (DotK).
     
 0.823
dotC
Defect in organelle trafficking lipoprotein DotC.
  
   
 0.821
Lcin_2001
IcmC (DotE).
     
 0.795
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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