Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdtC_2Integral membrane protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1011 aa)    
Predicted Functional Partners:
mexA
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.980
acrA
RND efflux membrane fusion protein, acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.932
mdtE_1
Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.925
czcB
Cation efflux system protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.869
lmxE
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.800
mdtA
Multidrug efflux system, subunit A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.762
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.757
mdtE_2
Hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.747
bepF
Membrane-fusion protein involved in transport; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  0.739
acrA_1
Membrane-fusion protein AcrA.
  
  0.687
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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