glk protein (Legionella cincinnatiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

glk

Glucokinase; Belongs to the bacterial glucokinase family. (334 aa)

Predicted Functional Partners:

zwf

0.991

eda

0.986

edd

0.980

pgl

0.967

pgi

0.966

Lcin_2019

0.946

eda_1

0.919

tkt

0.899

algC

0.884

treF

0.874

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_2019	glk	Lcin_2019	Lcin_2022	Glucan 1,4-alpha-glucosidase.	Glucokinase; Belongs to the bacterial glucokinase family.	0.946
Lcin_2019	treF	Lcin_2019	Lcin_1053	Glucan 1,4-alpha-glucosidase.	Alpha,alpha-trehalase.	0.542
algC	eda	Lcin_3406	Lcin_2021	Phosphomannomutase.	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	0.856
algC	eda_1	Lcin_3406	Lcin_1265	Phosphomannomutase.	Keto-hydroxyglutarate aldolase.	0.849
algC	glk	Lcin_3406	Lcin_2022	Phosphomannomutase.	Glucokinase; Belongs to the bacterial glucokinase family.	0.884
algC	pgi	Lcin_3406	Lcin_1401	Phosphomannomutase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.901
algC	pgl	Lcin_3406	Lcin_2024	Phosphomannomutase.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.412
algC	tkt	Lcin_3406	Lcin_0111	Phosphomannomutase.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.869
algC	zwf	Lcin_3406	Lcin_2025	Phosphomannomutase.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.	0.868
eda	algC	Lcin_2021	Lcin_3406	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	Phosphomannomutase.	0.856
eda	eda_1	Lcin_2021	Lcin_1265	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	Keto-hydroxyglutarate aldolase.	0.890
eda	edd	Lcin_2021	Lcin_2023	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.	0.997
eda	glk	Lcin_2021	Lcin_2022	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	Glucokinase; Belongs to the bacterial glucokinase family.	0.986
eda	pgi	Lcin_2021	Lcin_1401	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.893
eda	pgl	Lcin_2021	Lcin_2024	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.907
eda	zwf	Lcin_2021	Lcin_2025	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.	0.922
eda_1	algC	Lcin_1265	Lcin_3406	Keto-hydroxyglutarate aldolase.	Phosphomannomutase.	0.849
eda_1	eda	Lcin_1265	Lcin_2021	Keto-hydroxyglutarate aldolase.	2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.	0.890
eda_1	edd	Lcin_1265	Lcin_2023	Keto-hydroxyglutarate aldolase.	6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.	0.969
eda_1	glk	Lcin_1265	Lcin_2022	Keto-hydroxyglutarate aldolase.	Glucokinase; Belongs to the bacterial glucokinase family.	0.919