plaA protein (Legionella cincinnatiensis) - STRING interaction network

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Score

plaA

Lysophospholipase A. (307 aa)

Predicted Functional Partners:

sdhA_1

0.755

lapB

0.754

lspK

0.704

lspD

0.704

lipA

0.701

lssX

0.700

lspF

0.693

pilD

0.690

lspI

0.646

Lcin_2038

0.518

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_2038	plaA	Lcin_2038	Lcin_2037	ATPases involved in biogenesis of archaeal flagella.	Lysophospholipase A.	0.518
lapB	lipA	Lcin_3290	Lcin_3076	Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.733
lapB	lssX	Lcin_3290	Lcin_3264	Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	Legionella secretion system protein X; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.754
lapB	plaA	Lcin_3290	Lcin_2037	Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	Lysophospholipase A.	0.754
lapB	sdhA_1	Lcin_3290	Lcin_0671	Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.766
lipA	lapB	Lcin_3076	Lcin_3290	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	0.733
lipA	lssX	Lcin_3076	Lcin_3264	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Legionella secretion system protein X; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.998
lipA	plaA	Lcin_3076	Lcin_2037	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Lysophospholipase A.	0.701
lipA	sdhA_1	Lcin_3076	Lcin_0671	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.742
lspD	lspF	Lcin_2524	Lcin_0391	Type II protein secretion LspD.	Type II secretory pathway protein LspF.	0.932
lspD	lspI	Lcin_2524	Lcin_0394	Type II protein secretion LspD.	Type II secretory pathway protein LspI.	0.932
lspD	lspK	Lcin_2524	Lcin_0396	Type II protein secretion LspD.	Type II secretory pathway protein LspK.	0.936
lspD	pilD	Lcin_2524	Lcin_0254	Type II protein secretion LspD.	Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.764
lspD	plaA	Lcin_2524	Lcin_2037	Type II protein secretion LspD.	Lysophospholipase A.	0.704
lspF	lspD	Lcin_0391	Lcin_2524	Type II secretory pathway protein LspF.	Type II protein secretion LspD.	0.932
lspF	lspI	Lcin_0391	Lcin_0394	Type II secretory pathway protein LspF.	Type II secretory pathway protein LspI.	0.966
lspF	lspK	Lcin_0391	Lcin_0396	Type II secretory pathway protein LspF.	Type II secretory pathway protein LspK.	0.955
lspF	pilD	Lcin_0391	Lcin_0254	Type II secretory pathway protein LspF.	Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.952
lspF	plaA	Lcin_0391	Lcin_2037	Type II secretory pathway protein LspF.	Lysophospholipase A.	0.693
lspI	lspD	Lcin_0394	Lcin_2524	Type II secretory pathway protein LspI.	Type II protein secretion LspD.	0.932