Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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Co-expression
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[Homology]
Score
srfAASurfactin synthase subunit 1. (90 aa)    
Predicted Functional Partners:
tycC_2
Non-ribosomal peptide synthase.
 
 0.991
pksN
Peptide synthetase, non-ribosomal.
 
 0.955
tycC_1
Peptide synthetase, non-ribosomal.
 
 0.896
Lcin_1849
acyl-CoA synthetase.
 
 0.866
rkpA
Type I polyketide synthase WcbR.
 
 
 0.842
pksM
Polyketide synthase.
 
 
 0.834
Lcin_1779
Peptide synthetase, non-ribosomal.
 
 
  0.818
Lcin_2834
Peptide synthetase, non-ribosomal.
 
 
  0.786
pksJ
Polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.779
mbtH
MbtH-like protein.
 
  0.771
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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