STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frmCS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)    
Predicted Functional Partners:
frmA
Alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
tycC_2
Non-ribosomal peptide synthase.
   
 0.793
tycC_1
Peptide synthetase, non-ribosomal.
    
 0.733
Lcin_1849
acyl-CoA synthetase.
   
 0.721
Lcin_1446
LphB.
    
  0.697
adh
Threonine(-3-)dehydrogenase.
 
 
 
 0.694
pksN
Peptide synthetase, non-ribosomal.
    
 0.693
gloA
Lactoylglutathione lyase.
    
  0.673
fadH
2,4-dienoyl-CoA reductase.
  
 
 0.664
Lcin_0024
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
     
 0.633
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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