STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fleNFlagellar synthesis regulator. (289 aa)    
Predicted Functional Partners:
fliA
Sigma factor 28; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.995
fleQ
Transcriptional regulator FleQ.
 
 
 0.973
fleR
Two-component response regulator.
 
 
 0.971
flgD
Flagellar basal body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.956
gmr_3
Regulatory protein (GGDEF domain).
 
 
 0.917
cheA
Chemotaxis histidine kinase.
 
  
 0.729
cheB
Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.704
saeR
Two-component response regulator.
  
 
 0.613
Lcin_2400
Hypothetical protein.
       0.608
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
   0.584
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: low (22%) [HD]