yicO protein (Legionella cincinnatiensis) - STRING interaction network

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Score

yicO

Xanthine/uracil permease. (426 aa)

Predicted Functional Partners:

araB

0.699

Lcin_0024

0.620

psuK

0.584

iolCB

0.573

Lcin_2528

0.561

purE

0.550

purL

0.526

Lcin_2526

0.513

purM

0.481

purQ

0.479

Your Current Organism:

Legionella cincinnatiensis

NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lcin_0024	araB	Lcin_0024	Lcin_2959	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	L-arabinolactonase.	0.616
Lcin_0024	iolCB	Lcin_0024	Lcin_2955	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	IolC/IolB transferase kinase protein.	0.528
Lcin_0024	psuK	Lcin_0024	Lcin_1714	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Carbohydrate kinase, pfkB family.	0.568
Lcin_0024	yicO	Lcin_0024	Lcin_2527	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Xanthine/uracil permease.	0.620
Lcin_2526	yicO	Lcin_2526	Lcin_2527	Hypothetical protein.	Xanthine/uracil permease.	0.513
Lcin_2528	yicO	Lcin_2528	Lcin_2527	Hypothetical protein.	Xanthine/uracil permease.	0.561
araB	Lcin_0024	Lcin_2959	Lcin_0024	L-arabinolactonase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.616
araB	iolCB	Lcin_2959	Lcin_2955	L-arabinolactonase.	IolC/IolB transferase kinase protein.	0.482
araB	yicO	Lcin_2959	Lcin_2527	L-arabinolactonase.	Xanthine/uracil permease.	0.699
iolCB	Lcin_0024	Lcin_2955	Lcin_0024	IolC/IolB transferase kinase protein.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.528
iolCB	araB	Lcin_2955	Lcin_2959	IolC/IolB transferase kinase protein.	L-arabinolactonase.	0.482
iolCB	psuK	Lcin_2955	Lcin_1714	IolC/IolB transferase kinase protein.	Carbohydrate kinase, pfkB family.	0.727
iolCB	yicO	Lcin_2955	Lcin_2527	IolC/IolB transferase kinase protein.	Xanthine/uracil permease.	0.573
psuK	Lcin_0024	Lcin_1714	Lcin_0024	Carbohydrate kinase, pfkB family.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.568
psuK	iolCB	Lcin_1714	Lcin_2955	Carbohydrate kinase, pfkB family.	IolC/IolB transferase kinase protein.	0.727
psuK	yicO	Lcin_1714	Lcin_2527	Carbohydrate kinase, pfkB family.	Xanthine/uracil permease.	0.584
purE	purL	Lcin_2614	Lcin_2607	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	Phosphoribosylformylglycinamidine synthase II (FGAM synthase II); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...]	0.997
purE	purM	Lcin_2614	Lcin_2608	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	Phosphoribosylformylglycinamidine cyclo ligase.	0.998
purE	purQ	Lcin_2614	Lcin_2609	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...]	0.997
purE	yicO	Lcin_2614	Lcin_2527	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	Xanthine/uracil permease.	0.550