Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilZ_2Type IV pilus assembly PilZ. (185 aa)    
Predicted Functional Partners:
gmr_3
Regulatory protein (GGDEF domain).
  
 
 0.881
tycC_2
Non-ribosomal peptide synthase.
    
   0.778
Lcin_1398
DamX-related protein.
  
     0.768
iraA
Small-molecule methyltransferase IraA.
  
     0.762
secA_3
Coiled-coil protein.
  
     0.761
Lcin_3155
Ankyrin repeats (3 copies).
  
     0.758
Lcin_1831
Sphingomyelin phosphodiesterase.
  
     0.745
yggX
Protein that protects iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.719
Lcin_1637
Fe-S protein.
  
     0.714
Lcin_2804
Ankyrin repeat protein.
  
     0.709
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.