Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lcin_25963-beta hydroxysteroid dehydrogenase/isomerase. (327 aa)    
Predicted Functional Partners:
Lcin_2595
Zn-dependent hydrolase GumP.
  
  0.969
Lcin_2594
Coenzyme F390 synthetase FtsA.
 
     0.948
Lcin_2593
PAP2 superfamily protein.
  
 
 0.878
tycC_2
Non-ribosomal peptide synthase.
   
 0.868
fabH_4
3-oxoacyl-ACP synthase.
 
     0.866
Lcin_0503
Saframycin Mx1 synthetase B.
  
 0.823
Lcin_1849
acyl-CoA synthetase.
   
 0.780
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 0.778
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.761
skp
Outer membrane protein OmpH; Belongs to the skp family.
    
   0.745
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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