Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Lcin_2619Ras family GTPase. (307 aa)    
Predicted Functional Partners:
Lcin_0492
Protein phosphatase 2C.
  
 
 
 0.795
Lcin_3423
Putative solute carrier protein.
  
     0.766
Lcin_0284
Ankyrin repeat protein.
  
 
  0.709
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.702
Lcin_2580
Ectonucleoside triphosphate diphosphohydrolase.
  
     0.702
Lcin_1013
Serine carboxypeptidase.
  
     0.686
DWF
7-dehydrocholesterol reductase.
  
 
  0.668
Lcin_2476
Ankyrin repeat protein.
 
 
 0.665
hopD2
Tyrosine phosphatase II superfamily protein.
  
 
 0.658
Lcin_2762
Ankyrin repeat protein.
  
 
  0.655
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
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