close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheRMethyltransferase involved in chemotaxis (CheR domain). (293 aa)    
Predicted Functional Partners:
cheA
Chemotaxis histidine kinase.
 
 
 0.999
cheB
Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.997
frzCD
Chemotaxis signal transducer.
 
 0.993
Lcin_2631
Chemotaxis signal transduction protein (cheW domain).
 
 
 0.986
Lcin_2629
Chemotaxis signal transduction protein (cheW domain).
 
 
 0.975
gmr_3
Regulatory protein (GGDEF domain).
 
 0.951
cyaB
Guanylate/adenylate cyclase.
 
  
 0.947
arcB_2
Sensory box sensor histidine kinase/response regulator.
 
 0.931
arcB_1
Sensory histidine-kinase / response regulator.
 
 0.923
cph1
Two-component sensor histidine kinase.
 
 0.911
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: low (30%) [HD]