Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcin_2631Chemotaxis signal transduction protein (cheW domain). (199 aa)    
Predicted Functional Partners:
cheA
Chemotaxis histidine kinase.
 
 0.999
frzCD
Chemotaxis signal transducer.
 
 0.997
cheR
Methyltransferase involved in chemotaxis (CheR domain).
 
 
 0.991
cheB
Chemotaxis response regulator protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.991
Lcin_2629
Chemotaxis signal transduction protein (cheW domain).
 
  
 0.972
evgS_2
Sensor histidine kinase.
  
 0.969
arcB_1
Sensory histidine-kinase / response regulator.
 
 0.955
arcB_4
Sensory box histidine kinase/response regulator.
  
 0.949
gmr_3
Regulatory protein (GGDEF domain).
 
 0.943
cyaB
Guanylate/adenylate cyclase.
 
 0.918
Your Current Organism:
Legionella cincinnatiensis
NCBI taxonomy Id: 28085
Other names: ATCC 43753, CCUG 31230 A, CIP 103875, DSM 19233, L. cincinnatiensis, NCTC 12438, strain 72-OH-H
Server load: low (10%) [HD]